William Medill (February 1802 – September 2, 1865) was a 19th-century American lawyer and Democratic politician from Ohio.

After briefly serving as the second assistant postmaster general, Medill was appointed by President Polk as commissioner of Indian Affairs.

Elected to the new post of lieutenant governor of Ohio in 1851, Medill entered office in 1852, serving until the resignation of Governor Reuben Wood on July 13, 1853 to take up a Consular office in Chile.

Medill was re-elected in his own right in 1853, but was defeated in a bid for a second full term in 1855 by the anti-slavery Salmon P. Chase.

[6] This article incorporates public domain material from the Biographical Directory of the United States Congress