William Monroe High School was opened in 1925 as a one-story frame building with eight classrooms surrounding an auditorium.

The following year, 1983, the school was expanded to include a new gymnasium with a seating capacity of 1200, coach's offices, and an extra classroom.

In 1986, renovations occurred at the Greene County Technical Education Center, raising it to a contemporary state-of-the-art building.

In the summer of 1995, old sections of the building were renovated, and nine new classrooms and a large workroom were added to create a new science wing.

The school subsequently added eleven classrooms (mobile units) adjacent to the math/science wing.