William Talley House is a historic home located at Wilmington, New Castle County, Delaware.

It was built about 1770, as a one-room deep, two-room wide fieldstone dwelling.

The house has evolved to a 2+1⁄2-story, four-bay, rectangular dwelling with a steep gable roof.

It has two rectangular inside end brick chimneys covered with stucco that project through the gable peak.

This article about a property in Delaware on the National Register of Historic Places is a stub.