Willie "Poor Boy" Lofton (January 1897 – 1956 or c. 1962)[2] was an American Delta blues singer-guitarist.

Lofton never achieved much commercial success or recognition in his lifetime, but his rendition of Johnson's "Big Road Blues" has been revitalized on compilation albums.

[4][5] Lofton relocated to Chicago in 1934, recording and releasing the songs "Poor Boy Blues" and "It's Killin' Me" on Decca Records, with two additional songs from the session released in early 1935.

In January 1935, he recorded "Dirty Mistreater" and "Rainy Day Blues", the former of which adopted guitar lines from Johnson.

Lofton may have also been an uncredited guitarist for recordings completed by Kansas Joe McCoy later in the year.