Much like Alice, Wilma plays the strong-willed, level-headed person in her marriage, often criticizing Fred for pursuing his various ill-fated schemes.

Wilma is a good cook; one of her specialties is "gravelberry pie", the recipe for which she eventually sold to the "Safestone" supermarket chain.

[9] Wilma also enjoys volunteering for various charitable and women's organizations in Bedrock, shopping, and occasionally getting to meet the celebrities of their world, including Stony Curtis,[10] Rock Quarry,[11] and Jimmy Darrock.

When Pebbles is a teenager, Wilma gains employment as a reporter for one of Bedrock's newspapers, the Daily Granite (a spoof of the Daily Planet of Superman fame), under editor Lou Granite (a parody of The Mary Tyler Moore Show's Lou Grant).

While employed there, Wilma shares various adventures with prehistoric superhero Captain Caveman, who, in a secret identity, also works for the newspaper.

In The Flintstone Kids Wilma was voiced by Julie McWhirter Dees and Elizabeth Lyn Frasier at different points.