Various celebrities and politicians have visited throughout the restaurant's history, including singer Johnny Mathis, U.S. Sen. George Voinovich, R-Ohio, former Vice President Dan Quayle, and President Joe Biden (while vice presidential candidate in 2008).

In 2008, then vice presidential candidate Joe Biden stopped at Wilson's while on the campaign trail.

[6] Wilson's faced possible closure in 2009 due to the financial crisis and OSHA fines for their hamburger patty-molding machine's potential pinching and electrical shock hazards.

With training and safety precautions not affordable, then-manager Mike Fenbert ceased using the machine and began purchasing premade patties.

[2] By 2011, Maxie Curtis was replaced as an owner by Pam Balmer and her sister, Mary Ann Cramer, joining the other two co-owners.