Though it covered a wide range of genres and subject matters, Wimmen's Comix focused more than other anthologies of the time on feminist concerns, homosexuality, sex and politics in general, and autobiographical comics.

[1][2] Wimmen's Comix was a launching pad for many cartoonists' careers, and it inspired other small-press and self-published titles like Twisted Sisters, Dyke Shorts, and Dynamite Damsels.

[2] Contributors to issue #1 included Moodian, Michele Brand, Lora Fountain, Aline Kominsky, Lee Marrs, Diane Noomin, Sharon Rudahl, Trina Robbins, Shelby Sampson, and Janet Wolfe Stanley.

[9] Noomin and Kominksy subsequently put together Twisted Sisters, a one-shot published in June 1976 by Last Gasp which featured their own humorous and "self-deprecating" stories and art.

[10] (Many years later, many Wimmen's Comix' contributors, including Kominsky-Crumb, Noomin, Penny Van Horn, Carol Tyler, M. K. Brown, Phoebe Gloeckner, Carol Lay, Caryn Leschen, Leslie Sternbergh [ca], Dori Seda, Mary Fleener, and Krystine Kryttre, were published in Twisted Sisters: A Collection of Bad Girl Art [Viking Penguin] and Twisted Sisters: Drawing the Line [Kitchen Sink Press], both edited by Noomin.)

[2] This, and other political conflicts, along with financial difficulties and the increasing availability of other venues for independent female cartoonists, led to the end of the series after that issue.