The Victorian government's Wimmera Southern Mallee subregion[1] is part of the Grampians region in western Victoria.

Most of the Wimmera is very flat, with only the Grampians and Mount Arapiles rising above vast plains and the low plateaux that form the Great Divide in this part of Victoria.

[3][4] In the context of the Interim Biogeographic Regionalisation for Australia, the Wimmera is a sub-region of 2,145,380 hectares (5,301,300 acres) located within the Murray Darling Depression bioregion.

[citation needed] The smaller towns in the area are dying due to the declining value of primary products that dominate the region's economy.

[citation needed] Temperatures are hot in summer, ranging typically from a maximum of 30 °C (86 °F) to a minimum of 14 °C (57 °F), whilst extremes can be as high as 46 °C (115 °F).

One of the key preservation areas is contained within the Grampians National Park, which possesses many unusual wildflowers and the greatest diversity of flora and fauna in Victoria west of the Snowy River.

The Little Desert National Park, south of Nhill and west of Dimboola, is a large wilderness area of sand dunes that were too infertile for productive farming even with superphosphate and trace elements.