The Windsor Station project was entrusted to New York City architect Bruce Price, who chose a Romanesque Revival style for the building.

Windsor Station formed an integral component of Dominion Square as a diffuser of passenger traffic and as a central terminus for other modes of transportation.

[9] Via Rail was created in 1978 and took over the responsibility for operating intercity passenger trains of both Canadian National CN and CPR.

During Via's first months there was no operational change for CPR or CN trains, as they used their respective crews, routes, equipment and stations.

Amtrak's daily Montreal-New York City train (the Adirondack) continued to use Windsor Station until 1986.

Local services to Ottawa via Montebello and to Mont-Laurier, both of which had been transferred from CPR to Via, continued to use Windsor Station until they were cancelled in 1981.

After intercity passenger service was removed, Windsor Station continued to be a commuter rail terminal for the STCUM's (now the RTM's) Montréal/Dorion-Rigaud suburban train (now Vaudreuil-Hudson line).

Windsor Station also housed the headquarters of CPR and its parent company Canadian Pacific Limited until, after a corporate restructuring in the mid-1990s, the railway abandoned or sold most of its trackage east of Montreal and focused its activities in Western Canada.

The 13 terminal tracks running into Windsor Station and the overhead canopy have been removed, and replaced by a public square.