[1] Aiming to expand business opportunities and growth of its route network through bilateral agreements between countries in South and Central America, and mainly to face the expansion of its competitors, in 2021, Wingo, a Colombian low-cost airline owned by Copa Holdings, began the certification process to obtain a Panamanian air operator certificate.

[2][3] On August 12, 2021, Wingo Panama received its Air Operator Certificate (AOC) from the Civil Aviation Authority of Panama (AAC), being authorized to begin operations from the country, exploring opportunities in the domestic market and especially on international routes.

Flights are also operated under the IATA code P5, from its parent company Wingo.

[7][8] Since March 28, 2022, Wingo Panamá has been responsible for operations carried out under the Copa Cargo brand, a cargo subsidiary of Copa Holdings based at Tocumen International Airport, operating with a dedicated Boeing 737-800BCF to destinations such as Bogotá, Guatemala City, Havana, Managua, México City, Quito, San Jose, San Salvador, Santo Domingo and Kingston.

As of September 2024, Wingo Panama is operating to the following destinations: opf Copa Cargo opf Copa Cargo In September 2024, Wingo Panama's fleet will consist of only one cargo plane, while regular destinations will be operated by its parent company Wingo's fleet on an interchange basis between Colombia and Panama.