The route is commonly known as Pembina Highway between PTH 75 to Donald Street; as the Disraeli Freeway between Main Street and Talbot Avenue; and as Henderson Highway from Talbot to PR 204.

[2] The route begins at PTH 75 and Turnbull Drive in the suburb of St. Norbert and, as Pembina Highway, crosses the Perimeter Highway South, and runs north-northwest through Fort Garry (passing by the University of Manitoba).

Running north along the east bank of the Red River, it passes Hespeler Avenue and Chief Peguis Trail to Perimeter Highway North where it leaves the city as Provincial Road 204.

[3] The freeway includes the Disraeli Bridges, which stretch over the Red River and are integral in connecting the city's downtown and northeastern areas.

Funded through a Public-Private Partnership arrangement, the federal government provided $18.3 million (and an additional $53.3 m) for the infrastructure project, with the private Plenary Roads Winnipeg consortium being chosen to design, build, finance, and maintain the roadway.