It heads north on a curving route and passes through the communities of Cream and Praag.

The highway then turns northwest before curving back north into Gilmanton.

WIS 88 enters Gilmanton from the west and meets the western terminus of Wisconsin Highway 121 before turning north.

It meets the eastern terminus of Rustic Road 1 and heads north out of Gilmanton.

The highway crosses the Buffalo River before terminating at WIS 37 south of Mondovi.