State Trunk Highway 37 (often called Highway 37, STH-37 or WIS 37) is a 42.67-mile (68.67 km) state highway in Buffalo and Eau Claire counties in the west-central area of the US state of Wisconsin that runs generally north-northeasterly from Alma to Eau Claire.

The southern 23 miles (37 km) from Mondovi (the only significant settlement along the course of the highway) to Alma generally follows the course of the Buffalo River.

WIS 37 begins at Wisconsin Highway 35/Great River Road in Alma.

It then meanders in the northeast direction, connecting multiple county trunk highways along the way.

In Mondovi, it travels briefly eastward, concurrent with U.S. Route 10 before branching off north.