State Trunk Highway 95 (often called Highway 95, STH-95 or WIS 95) is a 73.76-mile (118.71 km) state highway in the west-central area of the US state of Wisconsin that runs east–west from near Neillsville to Fountain City.

WIS 95 also goes through Alma Center, Hixton, and Blair before going north–south on US 53 for 1.6 miles (2.6 km).

[2] Prior to 1926, no significant changes to the routing happened.

The Fountain City–Neillsville route was previously signed as WIS 53 before 1926.

Highways: US 53 (which caused WIS 53 to be decommissioned due to its route number being duplicated) and US 110 (which filled in the pre-1926 alignment of WIS 95).