The song "Drowning in a Daydream" was nominated for Best Metal Performance at the 40th Grammy Awards ceremony (which went to Tool for "Ænema").

[3] Wiseblood received a mixed-to-positive review from AllMusic writer Stephen Thomas Erlewine, who gave the album four stars out of five.

He described Wiseblood as the "closest Corrosion of Conformity have gotten to old-school heavy metal, yet their fondness for industrial soundbites and thrash-metal keeps the group sounding contemporary."

However, Erlewine stated that it "doesn't have half the hooks of its predecessor, which means it sounds great while its playing, but it disappears into the abyss once it's finished.

[9] The "Drowning in a Daydream" single includes a cover of Creedence Clearwater Revival's "Fortunate Son".