He had extensive contacts in Europe and supplied, among others, Erasmus of Rotterdam and Ulrich Zwingli.
In 1495 he printed in Basel (a commentary of Thomas Aquinas on the Pauline letters).
He had two bookstores in Basel and regularly attended fairs in Frankfurt, Lyon and Strasbourg.
Lachner had two sons and six daughters, along with three other children who died in 1519 from the plague.
In 1504 he published an edition of the works of Johannes Chrysostomos (printed by Jacob Wolff).