In the geographer Gerardus Mercator’s 1595 world atlas, the place was catalogued under the name WOLFZIM In 1844, within Wolfsheim’s limits, an important gold find was made at a princely grave from the time of the Migration Period (Völkerwanderung).

The find comes from the early 5th century and today can be found in the Wiesbaden Museum in the collection of Nassau antiquities.

On 15 May 1950, the Rheinsender (“Rhine Transmitter”) near Wolfsheim was brought into service by Südwestfunk SWF (now Südwestrundfunk SWR).

The municipality's landmark is the Rheinsender, a large medium-wave transmission facility that can be seen from a great distance, broadcasting on the frequency 1 017 kHz.

After the radiant power was reduced to 100 kilowatts, this fading was obsolete and the second mast superfluous.