[2][9] In August 2017, Quillette published an article in which five academics expressed support for James Damore, author of the "Google's Ideological Echo Chamber" memo.

[1][11] In 2018, Quillette published "Why Women Don't Code", which argued that a disparity of genders in computer science profession is due to innate sex differences.

[14] In August 2019, Quillette published a hoax article titled "DSA Is Doomed" submitted by an anonymous writer claiming to be a construction worker named Archie Carter who was critical of the organisation Democratic Socialists of America.

[16] Quillette has published articles supporting the "human biodiversity movement" (HBM),[17][18] which attempts to reintroduce ideas from eugenics and scientific racism into the mainstream.

[29] In a piece for Slate, Daniel Engber suggested that while some of its output was "excellent and interesting", the average Quillette story "is dogmatic, repetitious, and a bore".

[30] He wrote that it describes "even modest harms inflicted via groupthink—e.g., dropped theater projects, flagging book sales, condemnatory tweets—as 'serious adversity'", arguing that various authors in Quillette engage in the same victim mentality that they attempt to criticise.

[30] In an article for The Daily Beast, writer Alex Leo described Quillette as "a site that fancies itself intellectually contrarian but mostly publishes right-wing talking points couched in grievance politics".