Since the railway line opened ten years ago, it has transported 500 million passengers and provided over 500000 train services.

[4] When the line opened, the trains had a maximum in-service speed of 350 km/h (217 mph) according to Chinese sources.

[6][8] From December 28, 2009,[note 1] until Guangzhou South Station was opened on January 30, 2010, 28 passenger train services run on the line daily each way.

Nonstop trains, now cancelled, covered the 922 km (573 mi) long journey in a scheduled 02h57m (Southbound) or 02h58m (Northbound).

On October 1, 2010 during the National holidays, the railway line transported 118 thousand people in a single day.

[13] Since the railway line opened ten years ago, it has transported 500 million passengers and provided over 500000 train services.

On January 23, 2020, due to the COVID-19 pandemic and as part of the efforts to contain it, the Chinese authorities and city government announced that all services were suspended until further notice.

On December 9, 2009, a train achieved a top speed of 394.2 kilometres per hour (244.9 mph) and took 02h55m to travel from Guangzhou South to Wuhan during a test run.

[20] After opening of the high-speed railway, 13 out of 45 ordinary trains were cancelled, a decision criticized to have harmed the welfare of low-income workers.

While they were much slower than the new high-speed train, overnight service (which has been much reduced now) provided the convenience of traveling while sleeping.

With airlines reducing services on the high-speed routes, high-speed rail is the only effective time saving option during the short holiday breaks, such as Mid-Autumn Festival, May Day and Qing Ming Festival, making such trips more expensive.

The airline has aggressively cut fares, slashing the advance purchase price of flights between Wuhan and Guangzhou by almost half.

China Southern is expecting cooperation with the railway company to extend the market and develop more packaged travel products for the passengers.