This geographic feature was named by Robert Peary after Clarence F. Wyckoff, one of the founding members of the Peary Arctic Club in New York.

[1] When Robert Peary reached the area the weather was foggy and he assumed that the landform he stood upon was an island which he named "Clarence Wyckoff Island".

It stands in the outermost part of Wyckoff Land between Skaerbugt and Hellefisk Fjord.

[5] To the southwest the peninsula is attached to the mainland and to the northeast lies the Wandel Sea of the Arctic Ocean.

Cape Clarence Wyckoff is located 9 kilometres (6 mi) to the southeast of the eastern shore and Mount Clarence Wyckoff rises to the east, on the other side of Hellefisk Fjord.