Wyoming Highway 133 (WYO 133) is a 6.07-mile-long (9.77 km) north–south Wyoming State Road in north-central Fremont County providing travel to Pavillion.

Highway 133 proceeds due north toward Pavillion.

At almost 4.1 miles, the western terminus of Wyoming Highway 134 is intersected which heads east towards Shoshoni.

[1][2] Wyoming Highway 133 and Highway 134 provide a shorter alternate around US 26 and Riverton for traffic traveling between Jackson and Casper.

[3] The entire route is in Fremont County.