WYO 170 is predominantly an east–west highway, although it travels southeast to northwest for its last 5 miles.

Wyoming Highway 170 begins its northwestern end in an area called Hamilton Dome within the census-designated place of Owl Creek at Hot Springs CR 15.

[2] Highway 170 travels southeasterly from Hamilton Dome, locally named Hamilton Dome Road, and meets the eastern terminus of Wyoming Highway 174 approximately 5.5 miles south of Hamilton Dome.

Here WYO 170 turns east and is named Owl Creek Road.

WYO 170 will continue east for the remainder of its routing as it parallels Owl Creek along north edge of Wind River Indian Reservation.