The route passes through the northern portion of the Bear Lodge Mountains, part of the Black Hills National Forest.

When it gets to Devils Tower, it spawns a short spur, Wyoming Highway 110 (WYO 110).

There are no further major junctions and towns on the route, as WYO 24 crosses the state line and becomes SD 34.

[citation needed] In 2018, the speed limit on WYO 24 near Devils Tower was reduced from 65 miles per hour (105 km/h) to 45 mph (72 km/h) due to higher traffic volumes during peak travel seasons and the road's history of collisions.

[2] The monument had its highest visitor count in 2021, which saw traffic jams from the entrance that slowed a section of WYO 24.