Wyoming Highway 112 (WYO 112) is a 29.50-mile-long (47.48 km) state highway in north-central Crook County, Wyoming that runs from Hulett to the Montana-Wyoming State Line.

Wyoming Highway 112 begins its south end at Wyoming Highway 24 in Hulett.

From there WYO 112 travels north to Montana-Wyoming State Line.

The highway continues north from there a short distance as Montana Secondary Highway 326 to meet US 212 in Alzada, Montana.

[2][3] The entire route is in Crook County.