From its southern terminus WYO 430 heads northerly through remote terrain in the Horseshoe Basin for nearly 10 miles (16 km) before passing through a gap in Rife Rim.

[2] After continuing north for about another 10 miles (16 km), WYO 430 turns to head northwest for nearly 8 miles (13 km) before turning north again as loops around the south end of Cooper Ridge[3] Just over 10 miles (16 km) farther north, the highway turns to the northwest again to cross over the Salt Wells Creek and pass by the northern end of Sweeney Ranch as it crosses the South Baxter Basin.

About 15 miles (24 km) after its last turn to head northwesterly, WYO 430 enters Rock Springs on New Hampshire Street.

Just after passing over several sets of tracks of the Union Pacific Railroad, A Street turned north for several blocks before reaching the former northern terminus of WYO 430 at I-80 BL/US 20 Bus.

(North Center Street/Bridger Avenue) and the southern terminus of the former U.S. Route 187 (US 187) in the northern part of the downtown area.