X-linked recessive inheritance

X-linked inheritance means that the gene causing the trait or the disorder is located on the X chromosome.

The current estimate of sequenced X-linked genes is 499, and the total, including vaguely defined traits, is 983.

[1] In humans, inheritance of X-linked recessive traits follows a unique pattern made up of three points.

A few scholars have suggested discontinuing the use of the terms dominant and recessive when referring to X-linked inheritance.

[6] Stating that the highly variable penetrance of X-linked traits in females as a result of mechanisms such as skewed X-inactivation or somatic mosaicism is difficult to reconcile with standard definitions of dominance and recessiveness, scholars have suggested referring to traits on the X chromosome simply as X-linked.