XENA-AM 1450 came to air in 1949 as the second station of Radio Emisora Queretana, which owned XEJX 1250.
In 1962, XENA and XEJX moved to new facilities in Querétaro, inaugurated by Governor Manuel González Cossio, known as the Edificio Desarrollo Radiofónico (Radio Development Building).
Because the XHNA-FM and XHENA-FM call signs were taken, XENA became XHNAQ-FM with the added Q for the state (Querétaro).
The format lasted just seven months; on August 1, the station flipped to romantic as La Romántica.
On June 8, 2020, XHNAQ was one of seven stations to debut the new Lokura FM adult hits brand.