Two years earlier, in November 1964, the concession had been awarded to María Gloria Leticia Ávila y Vizcarra.
The station, operated by Carlos Caballero, was the fourth in the city and carried a wide-ranging music format, plus one of Querétaro's earliest radio newscasts.
XEXE broke from Grupo ACIR in 1989, moved its studio and transmitter to new facilities, and became known as "Radio Hit 1490 AM".
The station pioneered live broadcasts of lucha libre from the Arena Querétaro.
On October 1, 2016, it became Kiss FM as part of a marketing agreement with Multimundo, which took over operations from Integra, the group run by the Caballero Ávila family.