Xantphos is an organophosphorus compound derived from the heterocycle xanthene.

It is used as a bidentate diphosphine ligand and is noteworthy for having a particularly wide bite angle (108°).

[2] Illustrative of its wide bite angle, it forms both cis and trans adducts of platinum(II) chloride.

A related bidentate ligand with a greater bite angle is spanphos.

The ligand is prepared by double directed lithiation of 9,9-dimethylxanthene with sec-butyllithium followed by treatment with chlorodiphenylphosphine.