Kuli or Kholi or Chuli; Hebrew: יעקב כולי) was a Talmudist and biblical commentator of the seventeenth and eighteenth centuries who died in Constantinople on August 9, 1732.

He belonged to an exiled Spanish family, and was the grandson and pupil of Moses ibn Habib.

In 1727 Culi published his grandfather's work Shammot ba-Aretz, a book of notes on various portions of the Talmud.

Three years later he finally published Rosanes' voluminous Mishneh laMelekh, one of the most famous commentaries on Maimonides' Mishne Torah, enriched with numerous important notes of his own.

[1] This work, which is held in high regard by the Jews of the East, is a very elaborate encyclopedic commentary in Ladino, dealing with Jewish life in all its relations.

Because of the overwhelming popularity of the Me'am Loez, other prominent rabbis of Turkey took over this endeavor and completed the remaining volumes.