It contains a famous and visually stunning church, the building of which, led by Fray Alonso de Buenaventura, started in 1640 and took 60 years to complete.

Yaguarón is also notable as the birthplace of José Gaspar Rodríguez de Francia, dictator of Paraguay 1814–1840, whose strong authoritarianism earned him the name El Supremo.

In 1600, Fray Alonso de Buenaventura and his followers built an imposing church that still stands nowadays and is one of the most beautiful examples of Franciscan construction in Paraguay.

The road that leads to the cavern was venerated by the natives of the area, who told stories of a blond man that came much before the Spanish arrived and showed them how to cultivate the corn.

The Franciscan settled in Yaguarón and in the altar of the church they built can be appreciated the Hispanic-Guaraní style of the carvings the natives made by hand.