Previous efforts at bridge building were unsuccessful and the only way to get to Villa Busch, the administrative camp for the colony, was by boat.

[3] Yapacaní is located in the wettest region of the Santa Cruz department, situated on the border between the tropical montane rainforests of Amboró and Carrasco, the Amazon rainforests of the Chapare region, and the monsoonal llanos of western Santa Cruz and southwestern Beni.

While Yapacaní experiences a short dry season, rain is plentiful year round, and temperatures are generally warm to hot.

The small villages surrounding Yapacani produce rice, cane sugar, mandarin oranges, and other products.

A natural gas compound exists at the north end of the loop where there are two communities called Los Pozos and Patajusal.