[citation needed] Samuels moved to the Hebrew University of Jerusalem, where she worked toward an MSc in immunology.

She moved to Johns Hopkins University as a postdoctoral fellow in Bert Vogelstein's laboratory in 2003.

[1] The bank allowed her to analyse for mutations in melanomas, as well as offering hope for the identification of new drug targets.

[1] She returned to Israel as a researcher in 2012, where she established her own laboratory at the Weizmann Institute of Science.

[1] Samuels' research involves the use of DNA sequencing to identify genetic mutations in melanoma.