Pino has played in the minor leagues for the Minnesota Twins, Cleveland Indians, Toronto Blue Jays and Cincinnati Reds organizations.

At 30 years, 175 days, Pino is the oldest Twins starting pitcher to make his major league debut.

[2] Pino was optioned back to the AAA Rochester Red Wings on August 15, 2014, after making 10 starts and going 1–5 with a 5.37 ERA.

[4] On April 18, 2015, the same day he was called up from Triple-A,[5] he made his Royals debut, replacing starter Yordano Ventura after the latter was ejected in the fourth inning.

[6] He was optioned back to the minors on May 12,[7] after he blew a hold opportunity on May 9 with a throwing error in the bottom of the ninth against the Detroit Tigers.