The western terminus of the street is at Nepperhan Avenue (NY 983B), which connects to U.S. Route 9 (US 9) and New York State Route 9A (NY 9A).

The entirety of Yonkers Avenue is maintained by the New York State Department of Transportation as New York State Route 983C from Nepperhan Avenue to the Saw Mill River Parkway and New York State Route 984E from the Saw Mill River Parkway to Bronx River Road.

[2] A continuation of Yonkers Avenue east into Mount Vernon is signed as "To Mount Vernon Avenue" for the street it connects to on the opposite bank of the Bronx River.

The bridge carrying the street over the Bronx River Parkway and the Bronx River is maintained by Westchester County[3] and the 0.02-mile (0.03 km) long portion in Mount Vernon is designated but not signed as County Route 66A (CR 66A).

This article relating to roads in New York state is a stub.