York Run is a 5.89 mi (9.48 km) long 3rd order tributary to Georges Creek in Fayette County, Pennsylvania.

According to the Geographic Names Information System, it has also been known historically as:[1] York Run rises about 0.75 miles (1,2 km) southwest of Chadville, Pennsylvania,[2] and then flows southwest to join Georges Creek about 2.5 miles (4.0 km) southwest of Smithfield.

[3] York Run drains 17.16 square miles (44.4 km2) of area, receives about 43.3 in/year (1100 mm/a) of precipitation, has a wetness index of 373.76, and is about 48% forested.

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