The organization is based in Washington, D.C., and reaches out to 600 million youth (ages 15–24) in over 60 countries through the delivery of information, products, and social services.

Methods used to address issues include film, television, and radio; celebrity spokespersons; pop culture initiatives; theatrical productions; music; and sports.

Past recipients of the YouthAIDS Outstanding Achievement Award have included Sir Richard Branson, Sir Elton John, Annie Lennox, Judy McGrath, Nancy Pelosi, Archbishop Desmond Tutu, Senator Mary Landrieu, Senator Richard Lugar, and Bob Geldof.

[1][2] In the early 1990s, YouthAIDS founder Kate Roberts moved to Moscow, where she focused on launching the Russian version of Cosmopolitan magazine.

Through the sale of empowerment tags and lapel pins featured in ads with celebrities, ALDO has generated more than $10 million through this campaign, reaching 1.5 billion people in 25 countries.

Celebrities that have participated in the print campaign include Christina Aguilera, Salma Hayek, Cindy Crawford, Penélope Cruz, LL Cool J, Elijah Wood, Josh Lucas, and Ashley Judd.

They have used the donations from the campaign to support a youth center in Port-au-Prince, Haiti; and establish a partnership with an organization in Mozambique that offers peer education for young men, along with counseling and HIV testing.

[8][9] Over the course of ten years, Kiehl's, an American premium cosmetics company, has served as a major contributor of YouthAIDS, providing financial support, while developing educational programs that encourage philanthropy.

The concerts were edited and broadcast simultaneously as a 90-minute special on December 1, 2002 (World AIDS Day), in 170 countries and featured on all major news channels in Asia-Pacific, Europe, Latin America, Canada, Russia, and the US.

Additional films include India's Hidden Plague on the National Geographic Channel and Tracking the Monster – Ashley Judd and India.Arie Confront AIDS in Africa, presented by VH1 News.