Ysola Mary Best (15 November 1940 – 19 May 2007) was an Australian author and elder of the Yugambeh people.

In 1985, Best and her sister Patricia O'Connor successfully lobbied the University of Queensland to repatriate the skeletal remains of their ancestors from the Broadboach burial grounds.

The sisters worked towards establishing the Yugambeh Museum Language and Heritage Centre at Beenleigh which opened in 1995.

In 1994, she gave the opening address in Beaudesert at the Royal Historical Society of Queensland conference.

In 1980, Best and her husband moved to Tamborine Mountain, the traditional lands of the Wangerriburra clan of the Yugambeh people.