Before she started her career in the entertainment business, Wilson attended San Jose State University and majored in communications.

[citation needed] Wilson first entered comedy when she lost a bet and had to perform as a stand-up comedian at a friend's club.

In addition, Wilson also had a minor role in the 1995 comedy movie Friday as Smokey's blind date and appeared in films such as Poetic Justice, starring Janet Jackson, and the film parody Don't Be a Menace to South Central While Drinking Your Juice in the Hood.

In 1995, she got the most important role of her career: Andell Wilkerson, a supporting character on the sitcom Moesha, which starred one of her castmates from Thea, R&B singer Brandy Norwood.

Wilson's Andell character was the owner of The Den, a local teen hot spot on the show.