Zaisan (Kazakh: Зайсан ауданы, Zaisan audany) is a district of East Kazakhstan Region in eastern Kazakhstan.

The administrative center of the district is the town of Zaisan.

[3] Population: 37,924 (2013 estimate);[2] 34,593 (2009 Census results);[4] 39,556 (1999 Census results).

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