Desai is known for her portrayal of Sarala Ambar Raghuvanshi in Sajan Ghar Jaana Hai, Anmol Singh in Mooh Boli Shaadi, Rukmini in RadhaKrishn and Khyati Patel Kothari in Anupamaa.
[2] Zalak started her career at the age of 16 in serial Sajan Ghar Jaana Hai in 2009, just after she completed her 10th standard with 90 percentage aggregate from R.N.
[3][4][failed verification] She took a break to complete her 12th and graduation in B.Sc Biotechnology from Mithibai College (University of Mumbai) and returned in the Sony Entertainment Television's serial Mooh Boli Shaadi in 2015.
[6][7] In December 2019 she started playing goddess Rukmini alongside Sumedh Mudgalkar and Mallika Singh in Star Bharat's RadhaKrishn until it off-aired in January 2023.
Since January 2025, she is playing Khyati Patel Kothari opposite Rahil Azam in StarPlus' Anupamaa.