Saint Zayya (Syriac: ܡܪܝ ܙܝܥܐ) was a travelling mystic, holy man and healer who made his way from Palestine to the mountains of northern Mesopotamia and spreading Christianity with his disciple St. Tawor.

The Church of the East honours both Zayya and St. Tawor for their missionary efforts in northern Iraq and the region of Upper Dasen (modern Hakkâri province, Turkey) during the late 4th and early 5th centuries.

He is also the patron saint of travellers and the Jilu district, where he is buried, and is invoked for protection from hail, famine, plague, anger, illness, disease and the Angel of Death.

Zayya is often depicted in miniatures from manuscripts of the Book of Protection as an equestrian saint, spear in hand, and attacking the Angel of Death.

According to the calendar of the Church of the East, the birth of St. Zay'ā is celebrated on May 26, and a three-day rogation (fast) precedes the commemoration of his death on the first Wednesday of January.