[6] On 24 June 2022, Amdouni joined Basel's first team for their 2022–23 season under head coach Alexander Frei signing a two-year loan with an option for the club to buy.
[8] He played his first European match in the second qualifying round of the 2022–23 UEFA Europa Conference League 21 July, it was the home game in the St. Jakob-Park as Basel won 2–0 against Northern Ireland team Crusaders.
[15] On 19 July 2023, Amdouni signed for newly-promoted Premier League club Burnley on a five-year contract, for an undisclosed fee.
[22] He was called up by the senior Switzerland squad for the 2022–23 UEFA Nations League matches against Czech Republic, Portugal and Spain in June 2022.
[24] On 25 March 2023, Amdouni scored his first international goal against Belarus, as Switzerland won 5–0 in a UEFA Euro 2024 qualifying match.
[27] He appeared as a substitute in the team's first match, replacing opening goalscorer Kwadwo Duah in the 68th minute of the 3–1 win over Hungary in Cologne.