It is a spindly shrub with glabrous, three-part, clover-like leaves and clusters of up to thirty white flowers with four petals and four stamens.

Flowering occurs in spring and is followed by fruit which are glabrous capsules containing striped reddish-brown seeds.

[2] Zieria oreocena was first formally described in 2002 by James Armstrong from a specimen collected near Mount Zero in the Grampians and the description was published in Australian Systematic Botany.

The specific epithet is derived from Greek words meaning "a mountain" and "empty", referring to the Mount Zero area, where the type specimens were collected.

[3] Grampians zieria grows in woodland and shrubland on shallow rocky soils, as well as riparian scrubs on alluvium.