Zoe, Duncan, Jack and Jane is an American teen sitcom created by Daniel and Sue Paige, starring Selma Blair, David Moscow, Michael Rosenbaum, and Azura Skye that premiered on The WB network from January 17, 1999 and ended on June 11, 2000.

The show also starred Mary Page Keller as Zoe's single mother Iris during the first season from Main.

Scott Foley, fresh from Dawson's Creek, appeared in the pilot with the intention of having him star in the series as Zoe's love interest.

Gone was Keller as Zoe's mom, while Omar Gooding joined the cast as the foursome's friend Doug Anderson during the second season from Main.

After the series was cancelled, Michael Rosenbaum expressed disappointment with the fact that the network had cut his character's name out of the title for the second season.