Zofenopril (INN) is a medication that protects the heart and helps reduce high blood pressure.

It is an angiotensin-converting enzyme (ACE) inhibitor.

[1] In small studies, zofenopril appeared significantly more effective in reducing hypertension than two older antihypertensive drugs, atenolol and enalapril, and was associated with fewer adverse effects.

[2][3] Zofenopril is a prodrug with zofenoprilat as the active metabolite.

[5] This drug article relating to the cardiovascular system is a stub.