She stated that she "struggled for weeks" to find the best way to make this information public, and ended up doing so while discussing Angelina Jolie's New York Times OpEd piece describing her own double mastectomy.
[9] She then joined WSNS-TV the following year as a reporter and anchor, making her the first Chicago on-air broadcaster to work at both English and Spanish-language stations simultaneously.
[10] Sambolin hosted Un Buen Doctor, a weekly medical series focusing on health issues affecting Latinos airing on cable stations internationally.
[9] Sambolin left WMAQ in November 2011 to co-anchor CNN's morning program Early Start alongside Ashleigh Banfield.
[11] On December 13, 2013 Sambolin signed off from Early Start stating the primary reason was for her children and to be closer to family in the Chicago area.