It is named Zwingerhaus in memory of the physician Theodor Zwinger, who bought the house in 1572.
[1] In 1375 a house in possession of Heinrich Zum Walpach was first mentioned[1] While in possession of the zum Walpach family, the garden of the Zwingerhaus reached the Pfeffergässlein (English:Pepperalley) at the bottom of the valley.
[2] In 1494 Rüsch sold the house to Morand von Brunn and his wife Maria Zscheckenbürlein.
[3] He was also planning to decorate the facade with a mural, for which Hans Bock the Elder The descentents of Zwinger lived in the house until 1686.
[3] In 1843 the main house of the estate at the Nadelberg 23a was bought by the city of Basel.