Álvaro Eugenio de Mendoza Caamaño y Sotomayor (14 November 1671 – 23 January 1761) was a Spanish aristocrat and Catholic priest who became Patriarch of the West Indies and a Cardinal.

He was Major chaplain of the Royal Monastery of La Encarnación, Madrid, and the king's Sumiller de cortina.

[1] His principal consecrator was Archbishop Domingo Valentín Guerra Arteaga y Leiba, Bishop of Segovia.

[3] The king gave him the red biretta of this rank in a ceremony on 16 August 1747 in the church of San Jerónimo el Real in Madrid.

[1] He was succeeded as Patriarch of the West Indies by Buenaventura Fernández de Córdoba Spínola, who was appointed on 6 April 1761.