(6S)-6-Fluoroshikimic acid

(6S)-6-Fluoroshikimic acid is an antibacterial agent acting on the aromatic biosynthetic pathway.

[1] It may be used against Plasmodium falciparum, the causative agent of malaria.

[2] The molecule is targeting the enzymes of the shikimate pathway.

This metabolic pathway is not present in mammals.

[3] The use of the molecule led to resistances in Escherichia coli.

Chemical structure of (6S)-6-fluoroshikimic acid
Chemical structure of (6 S )-6-fluoroshikimic acid